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Glucose synthase kinase 3 (GSK-3) prevents Akt activation via inhibitory phosphorylation of the rapamycin-insensitive companion of mTOR (Rictor)

Some people may experience mild digestive upset, such as nausea or bloating, especially when taking high doses on an empty stomach

However, given that this is the first pilot study to explore the clinical utility of serum GPX-3 concentration in patients with AAV, we believe that this study has clinical implications in that this identified a novel biomarker that can assess and estimate activity and damage caused by AAV at diagnosis, although confined to the time of diagnosis

Data availability Requests for data and materials should be addressed to the corresponding author